Ten New Labdane-Type Diterpenes from the Fruit of Vitex rotundifolia.
نویسندگان
چکیده
منابع مشابه
Ten new labdane-type diterpenes from the fruit of Vitex rotundifolia.
Ten new labdane-type diterpenes were isolated from the fruit of Vitex rotundifolia L. (Verbenaceae), along with a known diterpene, vitexilactone. Their chemical structures were determined on the bases of spectroscopic data.
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CONTEXT Vitex negundo Linn. (Verbenaceae) seeds are pepper substitute and occasionally used as a condiment for edible purposes. The seeds also find use for analgesia, sedation, rheumatism and joint inflammation in folk medicine. OBJECTIVE To isolate and characterize bioactive constituents from V. negundo seeds. MATERIALS AND METHODS The ethanol extract of V. negundo seeds was subjected to r...
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Five new labdane diterpenes (1-5) together with seven known diterpenes have been isolated from a methanol extract of the aerial parts of Aster oharai. Five new structures were determined as 7alpha-hydroperoxylabda-8(17),14-dien-13(R)-ol-4-O-acetyl-alpha-L-6-deoxyidopyranoside (1), 7alpha-hydroperoxylabda-8,14-dien-13(R)-ol-4-O-acetyl-alpha-L-6-deoxyidopyranoside (2), labda-7,14-dien-13(R)-ol-4-...
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Seven new labdane-type diterpenoids, vitextrifolins A-G (1-7), along with eight previously reported analogues, were isolated from the fruits of Vitex trifolia. The structures of 1-7 were elucidated by spectroscopic data interpretation. The isolates were evaluated for their cytotoxicity against four human cancer cell lines (A549, HCT116, HL-60, and ZR-75-30), but all were inactive (IC(50) < 5 μg...
متن کاملLabdane-Type Diterpenes, Galangalditerpenes A-C, with Melanogenesis Inhibitory Activity from the Fruit of Alpinia galanga.
In our continuing study of biologically active natural products from the fruit of Alpinia galanga (Zingiberaceae), we newly isolated three new labdane-type diterpenes, termed galangalditerpenes A-C (1-3), along with four known sesquiterpenes (4-7) and two diterpenes (8 and 9). The stereostructures of 1-3 were elucidated on the basis of their spectroscopic properties. The melanogenesis inhibitor...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2001
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.49.82